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Uses and effects of Artemisinin

Short Facts about Artemisinin

Artemisinin, a naturally occurring active ingredient, and its synthetically produced derivatives such as artesunate, artemether, and dihydroartemisinin are known in the medical world primarily for their effective role in the treatment of malaria. They show particularly high efficacy against Plasmodium falciparum, the most dangerous malaria pathogen in humans.

Unique to artemisinin is its chemical structure, which includes a peroxide bridge. This structure gives artemisinin the ability to act cytotoxic to various tumor cells. This property highlights artemisinin as a potential candidate in cancer research.

Moreover, artemisinin is known for its broad effect against a variety of pathogens. Its antibacterial properties have been demonstrated in both gram-positive and gram-negative bacteria. Also noteworthy are the fungicidal effects of artemisinin, particularly against fungi such as Candida albicans as well as foot and nail fungus.

Not only bacteria and fungi, but also various viruses prove to be susceptible to artemisinin. Studies have shown that it is effective against viruses such as hepatitis B and C, various herpes viruses, and the Epstein-Barr virus.

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Malaria

  • Preventive Use of Artemisinin: Although artemisinin is primarily used for the treatment of malaria, there are situations where it can also be used preventively. This is known as chemoprophylaxis and is particularly used by travelers to malaria areas. Preventive intake usually begins 3-4 days before entering the malaria area and continues for up to four weeks after leaving the area. It is important to note that chemoprophylaxis must be individually adjusted, depending on factors such as destination, duration of stay, existing resistances, and individual health condition. In addition to prophylaxis, physical protection measures such as mosquito nets, repellents, and covering clothing should always be used to minimize the risk of mosquito bites. For a longer stay in a malaria area, an alternative here can also be our ArtemiCure® 30:1 Artemisia annua full spectrum extract as the physical strain of continuous use of artemisinin becomes too great.

 

  • Therapies: Particularly effective in the fight against malaria tropica, the most dangerous form of malaria, caused by Plasmodium falciparum.


1. Diagnosis:
Before artemisinin is administered, a malaria infection must be diagnosed. This is usually done by microscopic examination of blood smears or by rapid tests that detect specific antigens of the malaria pathogen.

2. Choice of Medication:
Artemisinin is usually used in combination with other malaria medications. These combination therapies are known as artemisinin-based combination therapies (ACTs). Common combination partners are lumefantrine, mefloquine, or amodiaquine.

3. Treatment Plan:
The exact dosage and duration of therapy depend on the age and weight of the affected person as well as the severity of the infection. Treatment usually lasts 5 days.

4. Monitoring and Side Effects:
During therapy, attention should be paid to side effects and the effectiveness of the therapy. The most common side effects include headaches, dizziness, nausea, and vomiting.

5. Prevention of Relapses: For infections with Plasmodium vivax or Plasmodium ovale, additional treatment with primaquine may be required to prevent relapses, as these types of malaria parasites can persist in the liver.

It is important that malaria treatment is carried out under medical supervision, as improper use of artemisinin and other malaria drugs can lead to resistance development and treatment failure.


Use:

  • Preventive Use: Per day: 1 capsule of ArtemiCure - Artemisinin 98%
  • Therapeutic Use: Per day: 1 capsule of ArtemiCure - Artemisinin 98% in the morning and evening


Note: The statements made here regarding malaria therapy refer exclusively to malaria areas in Africa, Asia, and India and are recognized and reproduced in cooperation with the WHO and the respective health systems and governments.
For the European Union, these statements are not valid.
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Various Types of Cancer


The use of artemisinin and its derivatives in cancer is widespread in many regions outside Western medical practice, particularly in Asian, Indian, and Latin American regions. In these regions, artemisinin is used in both traditional and modern medical contexts for cancer treatment, based on various modern research approaches and traditional healing practices.

 

  • Effect: When artemisinin encounters iron, it generates free radicals that can damage cancer cells. Since cancer cells often contain more iron than normal cells, they are particularly sensitive to artemisinin. This is why an iron cure is advised before starting artemisinin therapy. Artemisinin can also interrupt the process of cell division in cancer cells at various stages, inhibiting their growth. In addition, it prevents the formation of new blood vessels in tumors, further limiting their growth. Artemisinin can also trigger programmed cell death, also known as apoptosis, in cancer cells.


1. Traditional Medical Foundations:
In Asian and Latin American countries as well as in India, artemisinin has long been used in traditional (TCM) medicine. This application is based on a holistic approach that emphasizes the balance of the body and natural processes.

2. Combination with Modern Therapy Approaches:
Artemisinin is often used in combination with chemotherapy. These approaches may differ from those common in Western medicine and often include traditional healing methods in aftercare.

3. Dosage and Administration:
The dosage and form of administration of artemisinin can vary and are often tailored to the individual needs of the patient. This is administered orally as capsules, but also in other forms such as tinctures or infusions.

4. Application in Various Types of Cancer:
Artemisinin is used to treat a variety of cancers, with specific application methods tailored to the type of cancer and the stage of the disease. Artemisinin cannot be used for brain cancer types, as it cannot cross the so-called blood-brain barrier.

5. Healing:
Since cancer patients are treated with artemisinin very early, the healing results are about 90%. In addition, in the aftercare, the circumstances of the disease are still being researched. This holistic therapeutic approach ensures a permanent cure of the patient. This type of treatment thus aims not only at the cancer but also at the entire body and mind.


It is important to note that medical practices and views vary in different parts of the world and that what is accepted and practiced in one cultural or geographical context may differ from what is common in other parts of the world. Patients should always seek expert medical advice and carefully weigh the various available treatment options.

  • Application:

Preparation for therapy: a 2-week iron cure
Therapeutic Use: Once daily 1 capsule of ArtemiCure - Artemisinin 98% - for 3 weeks, pause for 7-10 days. The cycle of intake then starts again from the beginning. This intake cycle repeats until the dose is used up, or at least 3 times in a row. During the pause cycles, iron should be taken again to prevent deficiency symptoms.
Aftercare: To counteract possible relapses, it is recommended to build up the immune system with Colostrum 60% IgG.

Note: The statements made here regarding cancer therapies refer to the majority of countries. Excluded from this are the following countries and state

communities: Australia, Canada, England, European Union, Switzerland, USA, and countries that have joined their health systems.

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HIV
- Effect: The use of artemisinin in HIV is an area that is currently the subject of many research studies, and there are already established and recognized treatment methods with artemisinin for HIV.

1. State of Research:
So far, research results have shown that artemisinin may have some effectiveness against HIV, but these findings are preliminary and require further confirmation through clinical studies.

2. Mechanism of Action:
It has been found that artemisinin inhibits the replication of the HIV virus. Possibly by influencing certain enzymes or metabolic pathways that the virus needs for its multiplication.

3. Combination Therapy:
In the treatment of HIV, a combination therapy is usually used, known as antiretroviral therapy (ART). There are considerations whether artemisinin could be a useful additional component in such therapies.

4. Dosage and Application:
Since there is no standardized treatment with artemisinin for HIV yet, the optimal dosage is still unknown. Any potential application should at least be strictly monitored (documented).

5. Support through Clinical Studies:
Further clinical studies are planned to further confirm the efficacy and safety of artemisinin in the treatment of HIV.

- Application:
Currently, there are two recommendations:
3 weeks morning and evening each a capsule of 250mg
3 weeks 1 capsule of ArtemiCure - Artemisinin 98% with 500mg, pause for 5 days, then the intake cycle starts again.
Note: The statements made here regarding HIV treatment refer to the majority of countries. Excluded from this are the following countries and state communities: Australia, Canada, China, England, European Union, Russia, USA, and countries that have joined their health systems.
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Microorganisms
Artemisinin is increasingly being researched and partially used to combat various microorganisms. Especially noteworthy is its broad effect against various pathogens. The antibacterial property has been proven for both gram-positive and gram-negative bacteria. The fungicidal effects were particularly confirmed for fungi such as Candida albicans as well as for foot and nail fungus. Artemisinin is also effective against numerous viruses. Its derivatives have proven effective, for example, in hepatitis B and C, herpes viruses, and the Epstein-Barr virus.

1. Mechanism of Action Against Microorganisms:
Artemisinin works by generating free radicals in the cells of microorganisms, leading to oxidative stress and ultimately the death of the cells. This mechanism is particularly effective against parasites like Plasmodium.

2. Bacterial and Viral Infections:
Although artemisinin is primarily effective against parasites, it has been shown that it can also work against some bacterial infections. However, research in this area is not yet advanced, and further studies are needed to establish the efficacy and safety of artemisinin against bacteria and viruses.

3. Dosage and Forms of Application:
The exact dosage and method of application of artemisinin in combating microorganisms vary depending on the type of infection and the specific properties of the respective microorganism. Therefore, in some cases, it is recommended to use our ArtemiCure® 30:1 Artemisia annua full spectrum extract, as this is not a monosubstance and thus has all the active ingredient combinations of the Artemisia annua plant.

4. Combination Therapies:
Artemisinin is often used in combination with other antimicrobial agents to increase effectiveness and reduce the risk of resistance development.

- Application:
Currently, there are no clear application recommendations in this area. Therefore, we recommend following the dosage instructions on the label.
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Good to Know: The plant Artemisia annua is one of the world's most important economic plants. There are hardly any other plants that combine more patents on active ingredients and combinations.